Host cell invasion by coccidian parasites

(here sporozoite of Eimerian type) 

Sporozoite of Eimeria type attaches to the surface of an intestinal epithelial cell

(other motile stages are merozoites - with apical complex - and microgametes - with 'perforatorium (Scholtyseck)' ). We find content of micronems (see sporozoite) in the intercellular space.

The 'apical complex' is responsible for invasion of the host cell

Sporozoite enters the host cell. Cytoskeleton is disintegrated and the parasite forms a pocket in the cytoplasm of the host cell called the parasitophorous vacuole (pV). Content of the rhoptries(?) (dense granules) is discharged into the pV. 
Sporozoite has entered the host cell enclosed by the parasitophorous vacuole.
One refractile body will disappear and the sporozoite transforms into a trophozoite in which multiplication of nuclei will start. 

Finaly merozoites of the first generation will develop by budding from a big multinucleate residual body. 

© 1996 - 2018

Contact - IMPRESS & Privacy Policy (GDPR)

NON COMMERCIAL USE ONLY!

CAVEAT EMPTOR - INFORMATION WITHOUT GUARANTEE!